Research Interest
Research in my laboratory focuses on cellular physiology of the neocortex both in the context of determining normal neocortical function as well as to gain insights into pathophysiological mechanisms underlying certain aberrant human conditions such as epilepsy.
Publications
- Kumar SS, Jin X, Buckmaster PS, Huguenard JR. Recurrent circuits in layer II of medial entorhinal cortex in a model of temporal lobe epilepsy. J Neurosci. 27:1239-1246. (2007)
- Kumar SS, Buckmaster PS. Neuron-specific nuclear antigen NeuN in not detectable in gerbil substantia nigra pars reticulata. Brain Res. 1142:54-60. (2007)
- Kumar SS, Buckmaster PS. Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy. J Neurosci. 26:4613-4623. (2006)
- Kumar SS, Wen X, Yang Y, Buckmaster PS. GABAA receptor-mediated IPSCs and α1 subunit expression are not reduced in the substantia nigra pars reticulata of gerbils with inherited epilepsy. J Neurophysiol. 95:2446-2455. (2006)
- Kumar SS, Huguenard JR. Pathway specific differences in subunit composition of synaptic NMDA receptors on pyramidal neurons in neocortex. J Neurosci. 23(31):10074-10083. (2003)
- Kumar SS, Bacci A, Kharazia VK, Huguenard JR. A developmental switch of AMPA-receptor subunits in neocortical pyramidal neurons. J Neurosci. 22(8):3005-3015. (2002)
- Kumar SS, Huguenard, JR. Properties of excitatory synaptic connections mediated by the corpus callosum in the developing rat neocortex. J Neurophysiol. 86(6):2973-2985. (2001)
- Kumar SS, Faber DS. Plasticity of first-order sensory synapses: Interactions between homosynaptic LTP and hetrosynaptically evoked dopaminergic potentiation. J Neurosci. 19(5):1620-1635. (1998)
- Silva A, Kumar SS, Pereda A, Faber DS. Regulation of synaptic strength at mixed synapses: Effects of dopamine receptor blockade and protein kinase C activation. Neuropharmacol. 34(11):1559-1565. (1995)
- Kumar SS, Geuz A. Adaptive Resonance Theory based adaptive pole placement for neurocontrollers. Neural Networks. 4:319-335. (1991)
- Obaid AL, Komuro H, Kumar SS, Sugimori M, Lin JW, Cherkskey BD, Llinas R, Salzberg BM. FTX, an HPLC-purified fraction of funnel web spider venom, blocks calcium channels required for normal release in peptidergic nerve terminals of mammals: optical measurements with and without voltage sensitive dyes. Biological Bulletin. 179(2):232. (1990)
- Komuro H, Obaid AL, Kumar SS, Salzberg BM. Slices of mouse suprachiasmatic nucleus with attached optic nerve: recording of glutaminergic and GABA-ergic synaptic potentials using a voltage sensitive dye. Biological Bulletin. 179(2):231. (1990)