Dr. Lisa Eckel is currently accepting new graduate students.
Dr. Lisa Eckel
Professor of Psychology and Neuroscience, Director of Interdisciplinary Program in Neuroscience
- PDB B437
- Obesity, eating disorders, neuroendocrine control of ingestive behavior, ovarian rhythms in behavior.
- Current Research
- Currently, there are two ongoing research programs in my laboratory. The first project investigates the mechanism underlying estradiol's ability to control food intake and regulate body weight in female rodents. To study this problem, we use an integrated approach involving behavioral, physiological, pharmacological, and molecular techniques. The interaction between estrogen and neuropeptides is of particular interest. A second project investigates the changes in neuropeptide secretion associated with activity-based anorexia, an animal model of anorexia nervosa. We are also interested in identifying behavioral patterns in rats that might increase the risk of developing activity-based anorexia.
- Recent Publications
Butler MJ, Perrini AA, Eckel LA (2021). The Role of the Gut Microbiome, Immunity, and Neuroinflammation in the Pathophysiology of Eating Disorders. Nutrients, 13(2):500. PubMed Loney GC, Eckel LA (2021). The Pattern of Fos-Like Immunoreactivity Expressed Within the Nucleus of the Solitary Tract Is Associated With Individual Variation in the Taste Quality of a Stimulus. Chem Senses, 6:bjab036. PubMed Butler MJ, Perrini AA, Eckel LA (2020). Estradiol treatment attenuates high fat diet-induced microgliosis in ovariectomized rats. Horm Behav, 104675. PubMed Ogden SB, Malamas MS, Makriyannis A, Eckel LA (2019). The novel cannabinoid CB1 receptor agonist AM11101 increases food intake in female rats. Br J Pharmacol, 176(20):3972-3982. PubMed Butler MJ, Eckel LA (2018). Eating as a motivated behavior: modulatory effect of high fat diets on energy homeostasis, reward processing and neuroinflammation. Integr Zool, 13(6):673-686. PubMed Butler MJ, Hildebrandt RP, Eckel LA (2018). Selective activation of estrogen receptors, ER Alpha and GPER-1, rapidly decreases food intake in female rats. Horm Behav, 103:54-61. PubMed Gassen J, Prokosch ML, Makhanova A, Eimerbrink MJ, White JD, Proffitt Leyva RP, Peterman JL, Nicolas SC, Reynolds TA, Maner JK, McNulty JK, Eckel LA, Nikonova L, Brinkworth JF, Phillips MD, Mitchell JB, Boehm GW, Hill SE (2018). Behavioral immune system activity predicts downregulation of chronic basal inflammation. PLoS One, e0203961. PubMed Keel PK, Eckel LA, Hildebrandt BA, Haedt-Matt AA, Appelbaum J, Jimerson DC (2018). Disturbance of gut satiety peptide in purging disorder. Int J Eat Disord, 51(1):53-61. PubMed Reynolds TA, Makhanova A, Marcinkowska UM, Jasienska G, McNulty JK, Eckel LA, Nikonova L, Maner JK (2018). Progesterone and women's anxiety across the menstrual cycle. Horm Behav, 34-40. PubMed Maske CB, Jackson CM, Terrill SJ, Eckel LA, Williams DL (2017). Estradiol modulates the anorexic response to central glucagon-like peptide 1. Horm Behav, 93:109-117. PubMed