Education
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Undergraduate Degree: Undergraduate Institution: Undergraduate Major: |
Bachelor of Science Michigan State University Psychology/Behavioral Genetics |
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Degree Program at FSU: Major Professor: |
Ph.D. Dr. Zuoxin Wang |
Research
Interest/Philosophy
My current research focuses on examining the underlying neural mechanisms of mating induced selective aggression in male and female voles (both monogamous and non-monogamous species). In the past two decades several investigators have used the vole model to study the neural, chemical, and genetic underpinnings of partner preference as an index of pair bonding. However, little is known about the neural circuitry, chemistry, and molecular genetic underpinnings of the maintenance of pair bonding. One of the most classical behaviors associated with the maintenance of pair bonding is the onset of selective aggression; where an animal will display intense selective aggression to any other conspecific animal (male or female) except with their familiar partner. Central neurochemicals dopamine, vasopressin, and serotonin in discrete brains areas including but not limited to the lateral septum, medial amygdala, anterior hypothalamus, and nucleus accumbens have been shown to play a significant role in aggressive behavior in several human, primate, and rodent species. Therefore, I am currently investigating the neural circuitry and neurochemistry associated with mating induced selective aggression in voles.
Techniques
In the laboratory, I employ behavioral testing (partner preference and resident intruder paradigms), immunocytochemistry (single, double, and triple fluorescence), scanning confocal/stereological microscopy, microdialysis, tract tracing, in-situ hybridization, receptor autoradiography, enzyme-linked immunosorbent assays, high-performance-liquid-chromatography, and behavioral pharmacology.
Collaborative Efforts
In collaboration with scientists at Michigan State University and University of California-Los Angeles, I participate in examining the genetic and environmental influences on the relationships between steroid hormones and sexually dimorphic behavior (including mental disease) during important developmental time periods, such as prenatal/perinatal/pubertal development, using both human and animal models. In addition to these efforts, we are also interested in the role of both environmental and biological influences on sex differentiation and orientation.
Neuroscience Mentoring/Community Outreach
In collaboration with several students and faculty at FSU and throughout Florida, we engage in a number of scientific outreach efforts. These include an annual brain bee for high school students, brain awareness week for K-12 students, families, educators, and administrators, as well as a neuroscience student mentoring program, and statewide traveling brain museum and neuroanatomy training program. If interested in learning more about and/or participating in any of the above activities please feel free to contact me via e-mail or by phone.
Outside Interests
Art; functional, abstract, and performance
Publications
- Gobrogge KL, Liu Y, Jia X and Wang ZX. Anterior hypothalamic neural activation and neurochemical association with aggression in pair bonded male prairie voles. J Comp Neurol. 502:1109-1122. (2007) PDF

