Education/Training:
M.S. 1996; Zoology, University of Berne, Switzerland
M.D.-Ph.D. 2000; Neurobiology, Prof. Imboden H. and Prof.
Luescher H.R. University of Berne, Switzerland
Postdoctoral training
2001; Prof. McKinley M., Howard Florey Institute, University
of Melbourne, Australia
2002 Prof. Freeman M.E., Florida State University, U.S.A.
Funding:
The Lalor Foundation, postdoctoral fellowship
Current Project:
Prolactin secretion: A joint computational/experimental study of
hypothalamus-pituitary interactions.
Teaching experience:
Neurobiology for graduate students, University of Berne,
Switzerland 1996 - 2000
Awards:
Swiss National Science Foundation award for a one-year fellowship
at the University of Melbourne, Australia 2001
Collaborator:
Prof. Richard Bertram, Department of Mathematics, Florida
State University
Professional affiliations:
Published peer reviewed journal articles:
Egli M, Bertram R, Sellix MT, Freeman ME (2004) Rhythmic
secretion of
prolactin in rats: Action of oxytocin coordinated by vasoactive
intestinal polypeptide of suprachiasmatic nucleus origin.
Endocrinology
(in press).
Sellix MT, Egli M, Henderson RP, Freeman ME (2004) Ovarian
steroid
hormones modulate circadian rhythms of neuroendocrine dopaminergic
neuronal activity. Brain Res 1005:168-185.
Egli M, Berger Th, Imboden H (2002) Angiotensin II influences
the
hyperpolarisation-activated current Ih in neurones of the
rat
paraventricular nucleus. Neurosci Lett 330:53-56.
Sunn N, Egli M, Burazin TCD, Burns P, Colvill L, Davern
P, Denton DA,
Oldfield BJ, Weisinger RS, Rauch M, Schmid HA, McKinley
MJ (2002)
Circulating relaxin acts on subfornical organ neurons to
stimulate water
drinking in the rat. Proc Natl Acad Sci USA 99:1701-1706.
Egli M, Laurent JP, Mosimann R, Felix D, Imboden H (2000)
Morphological
and immunocytochemical characterisation of electrophysiologically
investigated neurons in the PVN of the rat. J Neurosci Methods
95:145-150.
Software:
Software for Hypothalamus-Pituitary Interactions
The files run with the XPPAUT computer software. XPPAUT
is free, and runs on Unix, Linux, and Windows machines.
It can be downloaded from the website of Bard
Ermentrout .
This file contains the mathematical model described in Endocrinology
(2004) for the interaction of dopaminergic neurons, oxytocinergic
neurons, and lactotrophs. Endo_04.ode
Presentations:
Rhythmic hormone secretion in rats: A computational model
of the
hypothalamic mechanism controlling prolactin secretion.
Presented at the
Meeting of the American Mathematical Society (2004) Tallahassee,
FL.
Experimental and computational studies of the neural network
regulating
Prolactin release. Biomedical seminar at Florida State University
(2003)
Tallahassee, FL.
Angiotensin II influences the hyperpolarisation-activated
current Ih in
neurones of the rat paraventricular nucleus. Presented at
the
International Congress of Physiological Sciences (2001)
Christchurch, New
Zealand.
Morphological, immunocytochemical and electrophysiological
investigations
on the hypothalamus of the rat. Clinical-neurobiological
seminar (1998)
University Hospital Berne, Switzerland.
Three dimensional models from electrophysiologically investigated
neurons. Presented at the Swiss Society for Optics and Microscopy
(1998)
Fribourg, Switzerland.