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Dr. Marcel Egli
Associate Faculty
Ph.D: 2000; Neurobiology, University of Berne, Switzerland

Office BRF Building
Phone Number (850) 644-9807


Education/Training:
M.S. 1996; Zoology, University of Berne, Switzerland
M.D.-Ph.D. 2000; Neurobiology, Prof. Imboden H. and Prof. Luescher H.R. University of Berne, Switzerland

Postdoctoral training
2001; Prof. McKinley M., Howard Florey Institute, University of Melbourne, Australia
2002 Prof. Freeman M.E., Florida State University, U.S.A.

Funding:
The Lalor Foundation, postdoctoral fellowship

Current Project:
Prolactin secretion: A joint computational/experimental study of hypothalamus-pituitary interactions.

Teaching experience:
Neurobiology for graduate students, University of Berne, Switzerland 1996 - 2000

Awards:
Swiss National Science Foundation award for a one-year fellowship at the University of Melbourne, Australia 2001

Collaborator:
Prof. Richard Bertram, Department of Mathematics, Florida State University

Professional affiliations:

Published peer reviewed journal articles:

Egli M, Bertram R, Sellix MT, Freeman ME (2004) Rhythmic secretion of
prolactin in rats: Action of oxytocin coordinated by vasoactive
intestinal polypeptide of suprachiasmatic nucleus origin. Endocrinology (in press).

Sellix MT, Egli M, Henderson RP, Freeman ME (2004) Ovarian steroid
hormones modulate circadian rhythms of neuroendocrine dopaminergic
neuronal activity. Brain Res 1005:168-185.

Egli M, Berger Th, Imboden H (2002) Angiotensin II influences the
hyperpolarisation-activated current Ih in neurones of the rat
paraventricular nucleus. Neurosci Lett 330:53-56.

Sunn N, Egli M, Burazin TCD, Burns P, Colvill L, Davern P, Denton DA,
Oldfield BJ, Weisinger RS, Rauch M, Schmid HA, McKinley MJ (2002)
Circulating relaxin acts on subfornical organ neurons to stimulate water
drinking in the rat. Proc Natl Acad Sci USA 99:1701-1706.

Egli M, Laurent JP, Mosimann R, Felix D, Imboden H (2000) Morphological
and immunocytochemical characterisation of electrophysiologically
investigated neurons in the PVN of the rat. J Neurosci Methods 95:145-150.

Software:

Software for Hypothalamus-Pituitary Interactions
The files run with the XPPAUT computer software. XPPAUT is free, and runs on Unix, Linux, and Windows machines. It can be downloaded from the website of Bard Ermentrout .

This file contains the mathematical model described in Endocrinology (2004) for the interaction of dopaminergic neurons, oxytocinergic neurons, and lactotrophs. Endo_04.ode

Presentations:

Rhythmic hormone secretion in rats: A computational model of the
hypothalamic mechanism controlling prolactin secretion. Presented at the
Meeting of the American Mathematical Society (2004) Tallahassee, FL.

Experimental and computational studies of the neural network regulating
Prolactin release. Biomedical seminar at Florida State University (2003)
Tallahassee, FL.

Angiotensin II influences the hyperpolarisation-activated current Ih in
neurones of the rat paraventricular nucleus. Presented at the
International Congress of Physiological Sciences (2001) Christchurch, New
Zealand.

Morphological, immunocytochemical and electrophysiological investigations
on the hypothalamus of the rat. Clinical-neurobiological seminar (1998)
University Hospital Berne, Switzerland.

Three dimensional models from electrophysiologically investigated
neurons. Presented at the Swiss Society for Optics and Microscopy (1998)
Fribourg, Switzerland.